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" La Grippe " as a Bacterial Disease.

H. C. Markham, M.D.
JAMA. 1890;XIV(11):394. doi:10.1001/jama.1890.02410110034012.
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To the Editor:  —Doubtless few now living will again have opportunity to observe so typical an illustration of the behavior of " germs " as a pathogenetic factor, as now exists in the prevailing epidemic of so-called "la grippe." The symptoms are notably consistent with its accredited cause, and with those of other familiar diseases of its class. Its fidelity of expression through the mucous surfaces is only equaled by its thoroughness in omitting no part of the same. In observing its selection of the lachrymal, nasal, pulmonary, gastric and intestinal surfaces, the writer looked not elsewhere for effects, until the fourth instance of severe (in one grave) aural implications and abscess clearly proved its identity in this locality. It appears, that nothing shall be lacking in this disease, to impress all doubters with its genuine parentage. Age, sex, condition, occupation, locality, diathesis, are all and equally its subjects. As judged by


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