C. B., seaman, aged 36 years, native of Maine, was admitted to the U. S. Marine Hospital, at Boston, Mass., Feb. 14, 1888, with symptoms of ulcerative colitis. He had had diarrhœa for two years, the discharges being watery and occasionally mixed with mucus and blood. There was tenderness on pressure over the entire course of the colon, notably the ascending portion. Examination of the rectum with the speculum gave a negative result. Patient's appetite was poor and his appearance anæmic. Ordered opii pulv. and bismuth subnitr., milk diet, and rest in bed. Under this treatment there was some improvement of the intestinal symptoms.
April 4th. Had a chill, followed by fever and sweating. Had been complaining of pain in right hypochondrium for several days previously. From this time patient had irregular chills and sweats, with increased temperature. Tenderness developed over the hepatic region, and the area of hepatic dulness