This hypnotic has now been before the profession long enough to give some idea of its merits, and there is little discrepancy, thus far, in the accounts of its effects furnished by different observers. Administered in doses of from 15 to 30 grains it usually induces quiet sleep for several hours without subsequent unpleasant effects. Owing to its sparing solubility in water, it is slow in its action, an hour and a half to two hours usually elapsing before the full effect of the drug is experienced.
Dr. W. L. Worcester, Assistant Physician to the Arkansas State Lunatic Hospital at Little Rock, has communicated to us the results of trials of sulfonal which have been made there since the middle of November last. It has been administered to seventeen different patients, being nearly all the cases in which the use of hypnotics was thought advisable during that time. Only one