The quantitative modifications of the carbonic acid exhaled by diabetics under the influence of diet and medicines has been investigated by Livierato, of Genoa, his results being published in Archiv für experimentelle Pathologie, Bd. xxv, S, 161. The experiments were made on three diabetic persons, one man and two women, one of whom was obese. All the patients had had diabetes for several years, and each excreted about 500 grams of sugar a day (twenty-four hours). The carbonic acid exhaled was measured by Pettenkofer's method; the patient respired in a cabinet. The amount of sugar was determined by Wild's polarimetre. Livierato's results may be summarized as follows:
In diabetics on ordinary diet the excretion of carbonic acid is diminished by more than one-half. On a mixed diet, but with starch excluded, consisting of meat, milk, cheese and vegetables, the weight of the two thin diabetics diminished, while that of the