JAMA. 1912;LIX(13):1154-1156. doi:10.1001/jama.1912.04270090398003.
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Hunger pain is a sensation of gnawing distress in the stomach coming on several hours after meals. It varies greatly in its intensity and may be described as a mere soreness in the epigastrium, or it may assume the form of a burning pain of sufficient severity to occasion real suffering. It is often accompanied by a feeling of impatience and irritability of temper, which renders it difficult to continue work or to concentrate the attention. It prompts the patient to lie down and may be partially relieved by heat or gentle steady pressure on the epigastric region. It occurs in some cases three hours after meals and continues until the next meal is eaten; or it may persist for an hour or two and then abate without the ingestion of food. It is usually unaccompanied by eructation or regurgitation, but in its more severe grades nausea of some degree


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