—March 20, 1012, Mr. E. M. A., an instructor in the chemical laboratory of the Iowa State University, while etching glass with a 48 per cent. solution of hydrofluoric acid, sustained an injury to the thumb, index- and middle lingers of the right hand.Immediately following the accidental application of not more than 3 minims of the acid, the patient complained of a sharp stinging pain on the surface covered by the acid, which gradually gave way to a deep-seated penetrating pain which he described by the Norwegian word, gjennentraengende. Accompanying this deep penetrating pain were loss of appetite, a feeling of increased bodily warmth, and a restlessness which gradually merged into an intense nervousness as the pain became more severe. Locally the region attacked by the acid became blackened and sharply defined from the normal tissue.
—The patient was first seen eight hours after the occurrence of