Until recently the doctor and the liver have been comparative strangers. This all-important organ, in its clam-like shyness, has presented only its size, position and delicate anterior border for examination. The question, is the liver diseased, could only be answered in a most general way by our inability to reconcile a chain of symptoms with the determined conditions of other organs. I believe I speak conservatively when I say the greatest need of clinical medicine and surgery is simple and exact methods of determining the presence of pathologic conditions in the liver and pancreas and a knowledge of the functional activities of these organs.
I present here in the simplest and most direct manner the technic of two tests of liver function and their theoretic and practical interpretation. They have for some time been in routine use by the Neisser clinic in Vienna, where I have had ample opportunity to