The case reported below raises the somewhat interesting question as to whether or not the hookworm is ever a causative agent in appendicitis and appendiceal colic. That such may be the case seems both reasonable and probable, as there is no reason why the appendix should not be invaded by the parasite, its presence acting as an irritant, producing colic and in favorable conditions as a starting point for a true inflammation. A further investigation by the profession should be of some interest and of practical importance to physicians practicing in infected districts.
—Mrs. S., aged 19, was referred to me for operation on February 25 by Dr. W. V. Stough of this city. General history was good; menstruation normal. Some three months previous the patient had suffered an attack of severe pain in right side followed by tenderness, since which time she had suffered