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ACTIVITY OF COMMERCIAL SUPRARENAL PREPARATIONS

JAMA. 1910;LIV(9):710. doi:10.1001/jama.1910.02550350046003.
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We have frequently had occasion to call attention in these columns to the need of physiologic standardization of certain important remedies such as digitalis, ergot, and suprarenal preparations. Physiologic standardization of the antitoxins, from the introduction of these remedies, has been a sine qua non, and there is an increasing demand that tuberculin and other vaccines be standardized before being tried on the patient. The recent publications of Hale and Edmunds and other workers have shown that the need for more uniform preparations of digitalis is no less imperative.

Schultz1 has just published the results of a careful examination of samples of the suprarenal preparations on the American market which illustrates once more the need of more care in the methods of preparing or keeping this important drug. Of the six different products, only two were of the strength claimed; the others varied from 3.7 to 66.6 per cent,

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