JAMA. 1910;LIV(9):705-707. doi:10.1001/jama.1910.92550350001001o.
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Although in late years bacterial products prepared in one way or another have been used in almost every conceivable pathologic condition, and especially in localized inflammatory processes, there is little in the literature on the application of inoculation treatment to otitis media. It would seem from the fact that this is a strictly local disease, and from the ease with which the causative organisms are isolated in the majority of cases, that this condition would lend itself particularly well to treatment by specific vaccines. The fact of its use is mentioned by a number of writers, but little is said of the value of the treatment in this particular disease. For these reasons I desire to report the following cases:

Case 1.  —Private J. H., Hosp. Corps, U. S. A., aged 41. Date, Aug. 2, 1908.

History.  —At 15 the patient had discharge from right ear; at 25 had malaria; for


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