OBSERVATIONS ON ALIMENTARY ALBUMINURIA BY MEANS OF THE ANAPHYLAXIS REACTION

Alimentary albuminuria has commonly been assumed to be a simple filtration from the blood of a foreign protein, present in the blood only because it has been taken into the digestive tract in such large amounts that some of the protein has passed directly through the mucous membrane into the blood, without having been first decomposed into amino-acids and other cleavage products. The protein found in the urine was supposed to be the same as that which had been eaten in excess, both on theoretical grounds and because of the results of chemical investigations. The chemical methods available for the distinguishing of proteins so similar as serum albumin and egg albumin, however, are anything but satisfactory, and therefore the identity of the proteins found in the urine after eating large amounts of raw eggs was not positively established. With the discovery of the biologic test for proteins our resources