The following case carne under my care July 28, 1909 :
—Virginia C., negro woman, aged 23, field hand, married, has child 4 months old. Family history negative. Patient has had attacks of malaria; no syphilis; has always used corn-bread in preference to other breads.
—This began about May 20, 1909, with "sore mouth." Patient had considerable difficulty in eating on account of pain. About June 1 a skin lesion appeared on the proximal side of the palm of the right hand. This was followed in about a week by a similar lesion on the dorsal surface of the left hand. These lesions increased rapidly in area. They were thought to be due to burns, although patient could not remember having burned herself. The lips soon became affected with a moist lesion. Patient began losing flesh rapidly but continued to work