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June 19, 1909, Vol LII, No. 25 >
ARTICLE | June 19, 1909

PHAGOCYTOSIS IN RELATION TO ARNETH'S CLASSIFICATION OF NEUTROPHILES

J. E. POTTENGER, A.B., M.D.
JAMA. 1909;LII(25):1980-1981. doi:10.1001/jama.1909.25420510014002a.
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If the experience of perhaps most workers who have written on the subject is to be accepted, the opsonic index as a means of diagnosis and especially as a therapeutic guide is far from satisfactory.

Disregarding the possibility that much of this adverse criticism is due to incomplete mastery of detail, there still seems good theoretical ground for not accepting some of Wright's earlier views on the question. In disregarding the leucocyte entirely he seems to have done wrong, since various observers have called attention to the variability of phagocytic activity by leucocytes obtained from various sources—in certain stages of infection and in artificially induced leucocytosis. But as far as I can determine no one has offered a satisfactory explanation for this varied activity.

Believing that Arneth's classification1 of neutrophiles in conjunction with the phagocytic power of the neutrophile might throw light on this question, I made the following

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