Patient.
—C. L. was born March, 1870, of American parents, on a Yuba county ranch. His paternal grandfather, from Yorkshire, Eng., lost his life by drowning; his paternal grandmother died at 84 of senility; his maternal grandfather and grandmother died at 84 and 89, respectively, presumably of senility. The patient's father died at 54 of "spinal paralysis" after several years' invalidism. His mother, born in Baltimore, died at 58 of sarcoma of the ileum. He has two brothers living; one is well, the other suffers occasionally from "petit mal;" one brother died at nine years of age, the result of epilepsy of traumatic origin; one sister is alive and apparently normal in every respect.
History.
—The patient had measles and whooping cough in childhood. He attended school until he was 12 years of age, when he was vaccinated; the lesion caused thereby refused to heal for six months, according to