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Pharmacology

JAMA. 1909;LII(19):1511-1514. doi:10.1001/jama.1909.02540450043012.
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The complete pamphlet may be had on receipt of a stamped addressed envelope.
These four pages are reproduced in the complete pamphlet which may be had on receipt of a stamped addressed envelope.
Dr. Beates' letter appears in the complete pamphlet.
Dr. Sollmann's communication appears in the complete pamphlet.
The communication from Sadtler & Son to the referee appears in the complete pamphlet.
To test the ether solution it is only necessary to pour some of it in a test tube containing a little very dilute ferric chlorid solution and shake. The aqueous solution assumes a color proportionate to the amount of methylene-di-salicylic acid in the ether.
Having myself taken this quantity of ur-a-sol I feel justified in saying something concerning the taste of the stuff, although this is a point that hardly deserves the discussion it has received in the appended communications. The taste of a drug to a healthy person who takes it as an experiment is apt to be very different from the taste to a person who is sick and who believes or hopes that the drug will cure him. To me the stuff called ur-a-sol was very disagreeable, and I had the taste of it in my mouth the entire day. Only once did it have any nauseating effect. That again is, however, largely a matter of personal idiosyncrasy. It will be noted that Prof. Sadtler now admits a more pronounced salicylic taste (p. 12). It is rather curious that he should have obtained this impression from less than a gram, but not from a "pinch" of the product which has such a slight solubility as ur-a-sol.

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