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ARTICLE |

Black-Water Fever.

JAMA. 1909;LII(16):1278. doi:10.1001/jama.1909.02540420058018.
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ABSTRACT

This is an extensive monograph of 239 pages, giving a comprehensive view of the nature of blackwater fever, its distribution, theories concerning its cause, the larger part (all but the first 66 pages) being given over to the development of their own theory.

Four main theories are cited: First, that blackwater fever is a pernicious form of malarial attack. This has been shown to be incorrect by the fact that there is no evolution of the malarial parasites coinciding with the attack of blackwater fever. Second, that blackwater fever is quinin intoxication. Experience is altogether against the conception that quinin alone may be its cause. Quinin in non-malarial countries is not known to have such an action. Third, that blackwater fever is a distinct disease, due to some specific organism. No parasite other than the malarial, however, has been found in cases of the disease. Piroplasmas in particular have been

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