Patient.
—On Sept. 20, 1908, a young man of 28 presented himself complaining of a sore throat and giving the history of exposure to diphtheria three days previously. An examination of the throat showed a typical membrane on the right tonsil, a culture from which gave the Klebs-Loeffler bacillus. Externally the throat was tender to pressure and the cervical lymph glands were enlarged. The patient was nervous; temperature 100 F. and pulse 95. The examination was otherwise negative.
Reaction from Antitoxin.
—At 11:30 a. m. 2000 units of antitoxin were injected in the back with no especial discomfort to the patient. In about ten minutes the patient became restless, the face cyanotic and the respirations difficult. Gradually the respiratory distress became marked, the patient lying in a slightly raised position, with head extended, face cyanotic, expression agonized, nostrils dilated, the body limp and covered with cold sweat—the picture of suffocation.