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February 20, 1909, Vol LII, No. 8 >

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ARTICLE | February 20, 1909

DIRECT BACTERIAL TREATMENT OF THE COLON THROUGH THE VERMIFORM APPENDIX

JAMA. 1909;LII(8):641. doi:10.1001/jama.1909.02540340039008.
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The preliminary report of a case under this caption in this issue1 is of interest, not only on account of the fact that the bacteriology of the alimentary tract is now much to the fore, but because of the results realized in this case and the possibilities, both in a scientific and therapeutic way, that are suggested by the procedure. The normal flora of the colon has never yet been studied with a definiteness that is more than suggestive. The relation of flora to function of the colon is not yet determined. The influence, inhibitory or otherwise, of the alimentary secretions on various micro-organisms remains to be determined in their natural position. The possibility of replacing one flora with another and the results of such a change on the health of the patient are entirely undetermined questions. Some new light may be thrown on the mode of operation of

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BMJ 2010;341:c5893-c1494.
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