—I was first consulted in the case of Miss B., aged 19, November 29. She had headache, general malaise and loss of appetite, November 15, and these symptoms lasted for a week. At that time she was constipated and took two ounces of sodium and potassium tartrate. She then suffered from foul smelling diarrhea which persisted for three days and was followed by constipation. About November 22 the headache disappeared, though the general malaise remained, and that evening she had several chills, followed by a rise in temperature, for which she took three grains of quinin three times a day. Pain in the abdomen appeared November 26, and seemed to follow the transverse colon. It was of gradual onset and she applied a mustard plaster but without result.
—The patient was somewhat emaciated and very weak. The pupils were slightly dilated; the sclera was clear. The tongue had