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THE DIAGNOSTIC VALUE OF THE CUTANEOUS AND CONJUNCTIVAL TUBERCULIN REACTIONS

WILLIAM ENGELBACH, M.D.; J. W. SHANKLAND, M.D.
JAMA. 1909;LII(1):37-45. doi:10.1001/jama.1909.25420270037001j.
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In endeavoring to arrive at definite conclusions as to the diagnostic value of the recent local tuberculin reactions, we have made a study of the literature on this subject to May 1, 1908, to which we have added the results of personal observations on 1,242 cases. The review of the literature includes the opinions of nine authors on their results with animal experiments; the reports of 41 authors on 5,032 cases of all ages subjected to these reactions, 3,477 to the conjunctival reaction and 1,546 to the cutaneous reaction. Our own investigations were made on adults only at the St. Louis City Hospital and the St. Louis University Medical School. They consist of 499 cutaneous reactions and 743 conjunctival reactions on 125 positive tuberculous cases, 190 suspect tuberculous cases, 700 other diseases not tuberculous clinically and 90 clinically normal individuals. The sum total of all cases considered is 6,305.

ANIMAL 

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