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October 17, 1908, Vol LI, No. 16 >
ARTICLE | October 17, 1908

THE INOCULATION TREATMENT OF GONOCOCCUS VULVOVAGINITIS IN CHILDREN.

FRANK SPOONER CHURCHILL, M.D.; ALEX C. SOPER, M.D.
JAMA. 1908;LI(16):1298-1301. doi:10.1001/jama.1908.25410160008001a.
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Forty-one patients in all have received the inoculations. Other therapeutic measures, douching, etc., have been omitted during injections. We have been able to treat continuously only eighteen patients. Of the others, most have been taken out of the hospital by their parents before treatment was completed; a few have died. A patient has been called "cured" when all discharge has ceased and when four successive bacteriologic examinations of smears taken from the vagina failed to show the specific organism, these tests covering a period of seven to fourteen days. We use the term "cure" advisedly, well knowing the tendency of this disease to recur, after long periods of apparent quiescence. In order to make our results as reliable as possible, we have attempted to follow up all our patients, but with little success. We have recent reports on only 9 of them, distributed as follows: Four in their homes, 3

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