JAMA. 1908;L(24):1986-1987. doi:10.1001/jama.1908.02530500034004.
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It is now generally recognized that a certain percentage of persons who have had typhoid fever continue to harbor the bacilli for varying periods of time after their recovery. The proportion of such "carriers" is put variously at from 1.7 per cent, up to 5 per cent. The length of time that this condition may last is at present a matter of speculation only. The most extreme case thus far reported is one of the Strassburg carriers, a woman who had had typhoid fever thirty years previously and still harbored typhoid bacilli. Such cases are known as chronic "carriers" to distinguish them from the acute "carriers" who show the presence of typhoid bacilli in the discharges for short periods of time only. The first very striking history of a chronic carrier was reported about two years ago by Kayser1 of Strassburg. Here, as in most of the subsequent instances,


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