The Annual Report of the Surgeon-General of the Public Health and Marine-Hospital Service for 1907 has just been received. A comparison of these annual reports shows a steady and continuous broadening of the functions of this service, each year developing more work that relates directly to the public health of the nation, as compared with its original functions as the Marine-Hospital Service, those pertaining to the quarantine, and the care of the merchant marine. During the past year the work of the bureau has covered investigations into hook-worm disease, plague, tuberculosis, typhoid fever, milk supply, etc. Among its important functions, as it relates directly to medical practice, is supervision of the manufacture of vaccines, such as diphtheria antitoxin, antistreptococcus serum and antityphoid serum. In conducting this work, not only are the establishments putting out these products under more or less continuous supervision, but products bought in the open market in