In a brief paper intended merely to enumerate the eradicative measures in operation in San Francisco, I shall not touch on the economic importance of the problem to the city, state and nation. In this connection it should be mentioned that plague is considered by some epidemiologists as the most difficult of all diseases to eradicate; indeed, there are those who maintain that where the infection has once taken root, the disease never dies out entirely. The success which crowned the efforts of the health authorities of Oporto in 1899, Glasgow in 1901, Naples in 1903, and San Francisco in 1903 and 1904, renders this theory untenable. Let no one be discouraged by these prophecies of evil, but let him remember that whenever organized bodies, having the cooperation of the people, have taken the field the disease has been vanquished.
To be successful, the campaign of eradication must be based