In 1877 I was called to treat Mrs. H., æt, 32 living in the western part of Ohio, a malarial district. She was received into the St. Joseph's Hospital, at Fort Wayne, Ind., where I treated her for an enlarged spleen. In six weeks she left for her home, very much improved, the spleen being reduced almost to its normal size. In March, 1885,I was again called to visit her, in consultation. I found a large tumor occupying the lower portion of the abdominal cavity; it was believed to be an extra uterine fibroma. During the consultation I mentioned the prevoius history of the case, and the possibility of the tumor being a misplaced and enlarged spleen. She died July 20, 1885. I made the autopsy and discovered that the tumor was the spleen. It had gravitated downward until its lower portion occupied a portion of the pelvic cavity. The