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JAMA. 1887;IX(25):780-784. doi:10.1001/jama.1887.02400240012002.
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Presystolic Heart Murmurs.  —At the meeting of the Medical Society of London, on November 7, Dr. J. S. Bristowe read a paper on this subject. He divided mitral obstruction murmurs into three varieties, namely: 1, one beginning from the second sound and ceasing in the course of the diastolic period; 2, one occurring isolated in the diastolic period; and 3, the murmur (to which the names presystolic and auricular systolic are indifferently applied) lying along the diastole and running up to the first sound. He likened the sound of the last of these (which is usually louder and rougher than the others) to that of the trilled R, and the sound of the two to that of an untrilled R; but observed that, although they sufficiently often occurred, separately to merit individual description, they not infrequently coalesced, in which case the whole of the interval between the second and the


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