0
ARTICLE |

THE EFFECTS OF COCAINE ON THE CENTRAL NERVOUS SYSTEM.1

D. R. BROWER, M.D.
JAMA. 1886;VI(3):59-62. doi:10.1001/jama.1886.04250010067002.
Text Size: A A A
Published online

We have recovered from the primary effects of the brilliant discovery of Dr. Carl Koller, that sixteen months ago electrified the medical world, and can now reason together calmly and dispassionately about this powerful therapeutic agent.

I have been using in private and hospital practice the preparation of the coca leaf for about six years, and for about one year past the alkaloid cocaine, and have reached certain conclusions as to its beneficial and its baneful effects on the central nervous system, that I propose to present for discussion in this paper. I say beneficial and baneful effects, for my first proposition is, that it is as powerful for evil as it is for good.

First. Its effect upon the brain.  —In small doses, that is, three or four drachms of the infusion, or one-half to one grain of the alkaloid, it is one of the most certain and agreeable

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs