JAMA. 1885;IV(7):191. doi:10.1001/jama.1885.02390820023011.
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Berlin, Germany, Jan. 10, 1885.

Mr. Editor:  —The method of cultivating bacteria by the solid culture media, which is at present so largely occupying the attention of bacteriologists, particularly on the continent, is deserving of especial attention. I feel the more liberty to say this now,and to explain the method a little in detail, because, like many others of my countrymen, I had a prejudice in favor of liquid cultures, especially when made in hermetically sealed bulbs, which I had used for several years previous to my coming to Germany. I soon saw, however, that I had not fully understood the method of solid cultures, and that my objections, chiefly of the danger of the entrance of impurities, were more theoretical than practical, and that this method, on the other hand, does possess many special advantages,—for in no other way can a mixture of different forms of germs be so


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