To the Editor.
—In the Medical News & Perspectives article1 discussing challenges in conducting clinical trials, Dr Harlan comments that General Stonewall Jackson "probably died because of bloodletting and not from any wound he received." It is a matter of record that General Jackson was dropped from the litter during his evacuation and had an amputation at the shoulder joint, but actually died of pneumonia. I am sure that the general received bloodletting as part of the treatment for the pneumonia and that this procedure did not help him. On the other hand, if it were not for the wound, he would not have developed pneumonia and would not have died; thus, the Confederacy would not have experienced its tremendous loss.