We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Evidence for More Benefits of Cholesterol-Lowering Drugs

Andrew A. Skolnick
JAMA. 1997;278(13):1053. doi:10.1001/jama.1997.03550130019008.
Text Size: A A A
Published online


CLINICAL STUDIES have shown that cholesterol-lowering drugs—such as the statin class of pharmaceuticals—can dramatically reduce the risks of myocardial infarction (MI) and mortality from heart disease. Accumulating evidence suggests that these agents do more than just lower cholesterol to protect patients at risk for coronary artery disease.

The evidence suggests the drugs may help reduce inflammation at the site of the plaque, reduce the risk of thrombosis, help normalize endothelial function, and improve the vessels' vasodilatory function. Speaking at the "Summit on Cholesterol and Coronary Disease: The 2nd National Conference on Lipids in the Elimination and Prevention of Coronary Artery Disease," in Lake Buena Vista, Fla, B. Greg Brown, MD, PhD, professor of medicine and cardiology and director of the University of Washington School of Medicine's Atherosclerosis Research Laboratory, in Seattle, described some of these mechanisms that may lie behind the drugs' ability to protect coronary arteries.

Lipid Depletion  By


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.