This ambitious text addresses all types of vascular disease as well as hypertension. The first third (about 400 pages) is devoted to basic concepts of biology of the vasculature and to pathophysiologic mechanisms, material most useful to clinical investigators and academicians. The next 150 pages cover diagnostic methods for evaluation of persons with vascular disease. Here the clinician will find much useful information.
The remaining 650 pages covers a great deal of clinical material so that in some areas details of management that some readers would appreciate are not included. Specific deficiencies, in my opinion, are the incomplete discussions of acute peripheral arterial occlusion (less than one page) and of thoracic outlet compression, no mention of the international normalized ratio (INR) in the anticoagulant section, and omission of transcutaneous oxygen tension as a noninvasive test of ischemia and of transesophageal echocardiography in the evaluation of unexplained embolic peripheral arterial occlusion.