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Screening for Gestational Diabetes-Reply

M. Scott Magee, MD; Carolyn E. Walden, MS; Thomas J. Benedetti, MD; Robert H. Knopp, MD
JAMA. 1993;270(3):324. doi:10.1001/jama.1993.03510030048030.
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In Reply.  —Dr Ring asks about perinatal morbidity in pregnancies with one rather than the usual two abnormal GTT values that are diagnostic for GDM. Previous studies show that a single GTT abnormality by NDDG criteria is associated with increased perinatal morbidity.1,2 To investigate this question in our own data set, we first determined if individuals with one abnormal value by the NDDG criteria had increased perinatal morbidity. We previously found that 65 (3.2%) of the women screened had two elevated GTT values by NDDG criteria, the classical definition of GDM. An additional 60 women (3.0%) of those screened had one elevated GTT value by NDDG criteria. The macrosomia rate (birth weight, >4000 g) was 29% in the GDM group and 25% in the group with one abnormal value, consistent with previous reports.1,2 We then determined how many of the 60 individuals with one elevated NDDG value had


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