0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

HMG CoA Reductase Inhibitors and Quality of Life

John R. Downs, MC, USAF; Gerry Oster, PhD; Nancy C. Santanello, MD, MS
JAMA. 1993;269(24):3107-3108. doi:10.1001/jama.1993.03500240051020.
Text Size: A A A
Published online

To the Editor.  —The Air Force Coronary Atherosclerosis Prevention Study (AFCAPS) is an ongoing randomized, double-blind, placebo-controlled primary prevention trial to determine whether treatment with the 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG CoA) reductase inhibitor, lovastatin, will prevent coronary heart disease in persons with mild to moderate elevations of total and low-density lipoprotein cholesterol and low high-density lipoprotein cholesterol levels. A total of 6605 participants without clinical evidence of coronary heart disease are enrolled, including men aged 45 to 73 years and women aged 55 to 73 years. Participants will be followed annually for total coronary heart disease events during a minimum of 5 years.A trial of this size and duration provides an opportunity to evaluate the long-term impact of cholesterol-lowering drug treatment on patient quality of life (QoL). In fact, it may be argued that it is imperative to assess the impact of long-term pharmacologic therapy on QoL in asymptomatic

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();