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Drug Eruption Reference Manual

Larry E. Millikan, MD
JAMA. 1996;276(6):505. doi:10.1001/jama.1996.03540060081045.
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For many years in Europe, an excellent resource for the evaluation of cutaneous drug reactions has been a book published by Bruinsma, related to the drug reaction reporting services of the European Benelux countries. Reporting of additional and different reactions through a central registry is periodically updated, so this book provides an important resource for European physicians, both in ambulatory care and dermatology, on up-to-date impressions and diagnosis of putative drug reactions. At one time in the United States, the American Academy of Dermatology had, with the Food and Drug Administration, an adverse drug reaction reporting service, which provided a reasonable database, but the service has been discontinued for lack of funding.

More recently, Jerome Litt has taken on much of this effort and has accumulated, over the last several years, an increasingly useful book of lists of probable drug reactions tied in with literature sources. The acronym for Drug


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