We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Variability in Bone Mass Measurement

Pekka Kannus, MD, PhD; Harri Sievänen, PhD
JAMA. 1993;269(11):1386. doi:10.1001/jama.1993.03500110054028.
Text Size: A A A
Published online


To the Editor.  —We read with great interest the recent article by Recker et al.1 The authors concluded that gain in bone mass occurs in healthy young women during the third decade of life, with the median gain (expressed as a percentage per decade) ranging from 4.8% (forearm) to 12.5% (total body). They used median values instead of means because "the distributions for rates of change in bone mineral were not gaussian."However, a closer look at their Table 2, which presents the percentage changes in bone mineral per decade, makes the conclusion questionable. Namely, the 95% confidence intervals (CIs) for these median gains in bone mineral are extremely large, including very high negative values. For example, the CI for the 4.8% median gain in the forearm bone mineral density was from —25.7% to 25.6%, indicating that in the population the actual change can be anything from very high


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.