0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Cellular Immunity to Sperm in Infertile Women-Reply

Patricia M. McShane, MD; Isaac Schiff, MD; David E. Trentham, MD
JAMA. 1986;255(1):36. doi:10.1001/jama.1986.03370010038011.
Text Size: A A A
Published online

ABSTRACT

In Reply.—  We appreciate the interest of Dr Haas in our work and agree that it does not identify the nature of the epitope that was responsible for inducing the cellular response in our infertile patients. However, we continue to conclude that this determinant was of spermatic origin since the presence of contaminating nonsperm cells should have been identified by our search for Ia-positive material in our test antigen preparation and led to alloreactive responses in our in vitro assays. Ia-driven responses probably account for the data obtained by Rodriguez-Cordoba and Arnaiz-Villena, and the absence of such findings increases the likelihood that the abnormal reactivity in our study was elicited by spermatozoa.Identification of the spermatic antigens should be given a high priority in order to afford the potential of antigen-specific immunotherapy for these women in the future.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();