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ARTICLE |

Pregnancy and Dysplastic Nevus Syndrome-Reply

Arthur J. Sober, MD
JAMA. 1985;254(15):2063. doi:10.1001/jama.1985.03360150039015.
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In Reply.—  Dr Nichols is correct in his assertion that the effects of pregnancy on dysplastic nevi remain to be established. However, since dysplastic nevi are currently thought to be present in only 2% to 4% of the white population, the relatively reassuring data presented in the article of Foucar et al1 would seem to be applicable to the remaining 96% to 98% of women who do not have dysplastic nevi. Anecdotally, I have followed several women with dysplastic nevi closely through pregnancy without discerning significant clinical changes in their nevi. I have been recommending close follow-up at three-month intervals for this group during pregnancy.The relationship, if any, between pregnancy and cutaneous melanoma is not clear at this time. While I have seen several women who have developed aggressive primary melanomas during pregnancy, I have seen similar events in nonpregnant women and in men. What is needed is

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