We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......

Bad Ads: MRFIT Misinterpreted

Warren H. Gullen, MD; Paul M. Fischer, MD; John S. Edelsberg, MD; John W. Richards Jr, MD; Jesse L. Steinfeld, MD
JAMA. 1985;254(4):504-505. doi:10.1001/jama.1985.03360040054013.
Text Size: A A A
Published online


To the Editor.—  We feel that the medical and scientific community should be aware of advertisements recently placed by tobacco interests in publications like Newsweek, Time, and the Washington Post. These ads interpret the results of the Multiple Risk Factor Intervention Trial (MRFIT) in such a way as to cast doubt on a causal relationship between smoking and coronary disease. The main "error" in the ad is to overlook the fact that the control group was "contaminated" (ie, a number of subjects in the control group altered their life-styles, including smoking behavior, without the extra special attention by the project staff). Thus, the study turned out to be a comparison between two methods of intervention and not between smoking and not smoking. Indeed, if one looks at those persons who actually quit and did not quit smoking in the groups who received and did not receive special attention by the


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.