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Alcohol, Nutrient Intake, and Hypertension-Reply

H. W. Gruchow, PhD; K. A. SOBOCINSKI, MS; J. J. Barboriak, ScD
JAMA. 1985;254(4):504. doi:10.1001/jama.1985.03360040053011.
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In Reply.—  We agree with Dr Holden that sodium intake probably has a much greater effect on blood pressures in salt-sensitive persons than in others. However, this does not rule out the possibility that higher sodium intakes contribute to elevated blood pressures in nonsensitive persons or that sodium might interact with other nutrients to increase blood pressures. The objective of our study was to assess the relative importance of dietary factors. Our analysis identified sodium as the nutrient having the strongest association with systolic blood pressure for the total study cohort and alcohol and sodium as having the strongest associations with systolic blood pressure for drinkers.Although a probability of less than 05 is footnoted in the tables displaying these results, the actual probability for the sodium-blood pressure association for the total study cohort is P=.00064 (F=11.675, with 1 and 9,549 df); for drinkers, P=.000007 (F=20.193, with


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