0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Hepatitis B Vaccination and AIDS

Shunichi Kato, MD; Hiroyuki IWASAKI, MD; Mikio Kimura, MD; Yasushi Togo, MD
JAMA. 1985;254(1):53. doi:10.1001/jama.1985.03360010059008.
Text Size: A A A
Published online

To the Editor.—  Articles about the relationship between hepatitis B vaccination and acquired immunodeficiency syndrome (AIDS)/human T-cell leukemia (lymphotropic) virus type III infection have often appeared in The Journal. In LEADS FROM THE MMWR in the Jan 4, 1985, issue,1 evidence confirming the absence of AIDS transmission by this hepatitis B vaccine was stated to be the following: (1) The AIDS virus is specifically inactivated by the inactivation procedures used in the vaccine's manufacture. (2) The vaccine contains no detectable AIDS virus nucleic acid sequence. (3) The serologic markers of infection with AIDS virus are not observed in vaccine recipients.

Study.—  In Japan, we studied Merck's Heptavax-B (lot 2374) in 74 health care workers who had no history of hepatitis B infection and determined, in addition to the safety and antigenic potential of the vaccine, the percentage of T-cell and B-cell subsets (OKT3, OKT4, and OKT8), the OKT4/OKT8 ratio,

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();