We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......

Bacteriuria: Colonization or Infection-Reply

Walter E. Stamm, MD; Richard Daifuku, MD
JAMA. 1985;253(13):1879. doi:10.1001/jama.1985.03350370058018.
Text Size: A A A
Published online


In Reply.—  Dr Kozinn and colleagues call attention to the semantic confusion that exists regarding the terms used to define UTI in asymptomatic catheterized patients. Ideally, one would like to distinguish between colonization, asymptomatic infection, and symptomatic infection.1 Colonization is usually defined as the multiplication of organisms in or on a host without apparent evidence of invasiveness or tissue injury, while clinical, histologic, or immunologic evidence of host injury or invasion accompanies infection.1 The distinction between colonization and infection in the urinary tract thus rests on (1) the presence of symptoms or signs indicating tissue invasion, (2) the presence of pyuria and/or hematuria, (3) a serological response, or (4) cystoscopic or histologic evidence of mucosal injury. It is not clear that any quantitative level of bacteriuria in catheterized patients correlates with infection rather than colonization. Indeed, patients with lower bacterial counts generally progress to higher counts (≥105


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.