Human Gene Therapy

Perrin C. White, MD; Mark E. Funk, MA
JAMA. 1992;267(17):2386. doi:10.1001/jama.1992.03480170112046.
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Gene therapy, the introduction and expression of exogenous genetic material, is an approach of great potential for the correction of inherited or acquired metabolic defects. Growing scientific interest is revealed in the growth of its literature: in MEDLINE, only 13 articles on human gene therapy were indexed from 1975 through 1981. From 1982 through 1986 this number had grown to 81. And from 1987 through the spring of 1991, 400 articles appeared.

This intensifying interest has inspired a new specialty journal, Human Gene Therapy. To our knowledge the first journal devoted solely to the topic, it aims to be a "resource for current information as well as a repository for future reference" for both scientific matters and "the broader social issues" relating to human gene therapy. The editor-in-chief, W. French Anderson of the National Heart, Lung, and Blood Institute, is one of the leaders in this nascent field. Articles on


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