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Respiratory Cryptosporidiosis in the Acquired Immune Deficiency Syndrome Use of Modified Cold Kinyoun and Hemacolor Stains for Rapid Diagnoses

Pearl Ma, PhD; Thelma G. Villanueva, MD; David Kaufman, MD; John F. Gillooley, MD
JAMA. 1984;252(10):1298-1301. doi:10.1001/jama.1984.03350100028024.
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We report three cases of primary intestinal cryptosporidiosis with bilateral interstitial pneumonia. The diagnoses were made using two rapid (one-minute) staining procedures, modified cold Kinyoun's solution and a Hemacolor set, on touch preparations of lung biopsy material, sputum, and stool. Intracellular cryptosporidia oocysts in alveolar macrophages suggest possible hematogenous spread of this agent. Opportunistic cryptosporidiosis should be included in the differential diagnosis of pneumonia in patients with acquired immune deficiency syndrome.

(JAMA 1984;252:1298-1301)


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