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Gastroparesis With Multiple Sclerosis

Yogesh K. Gupta, MD
JAMA. 1984;252(1):42. doi:10.1001/jama.1984.03350010022007.
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To the Editor.—  Multiple sclerosis is one of the more common chronic neurological disorders characterized by pleomorphic clinical presentation determined by the location of foci of demyelination. The lesions may vary in diameter from less than 1 mm to several centimeters, affecting principally the white matter of the brain and spinal cord. Recent studies1 demonstrated abnormal colonometrograms and absent postprandial colonic motor and myoelectric responses suggesting visceral neuropathy in patients with advanced multiple sclerosis and severe constipation. We recently saw a patient with multiple sclerosis who had gastroparesis.

Report of a Case.—  A 42-year-old man with multiple sclerosis diagnosed at 28 years of age was admitted to the Veterans Administration Medical Center, Albany, NY, for complaints of fullness of the stomach after meals, followed by nausea and vomiting. There was no abdominal pain, hematemesis, melena, weight loss, loss of appetite, or early satiety. The patient was admitted for shortness


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