0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Severe Hypertension and Lithium Intoxication

Joseph Michaeli, MD; Drori Ben-Ishay, MD; Ricardo Kidron, MD; Haim Dasberg, MD
JAMA. 1984;251(13):1680. doi:10.1001/jama.1984.03340370020009.
Text Size: A A A
Published online

To the Editor.—  Although lithium salts have become valuable psychopharmacotherapeutic agents, their use is limited by numerous adverse effects.1 In a survey2 of 123 patients with lithium intoxication, mild hypertension was reported in only two patients. We wish to describe a patient with severe hypertension that occurred during acute lithium intoxication.

Report of a Case.—  A 36-year-old woman with long-standing manic depression was hospitalized because of worsening of her depression. During previous admissions and in the course of two pregnancies she had been normotensive. At the time of admission she was receiving lithium carbonate, 1,200 mg daily; therapy had been started three months earlier. Admission BP was 110/55 mm Hg, and her plasma lithium level was 0.5 mmole/L (therapeutic range, 0.5 to 1.5 mmole/L). Because of her psychiatric deterioration, the lithium dose was doubled to 2,400 mg. One week later, the patient became confused, dysarthric, and ataxic and

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();