We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

The Efficacy of Mammography and Screening for Breast Cancer-Reply

Karla Kerlikowske, MD; Deborah Grady, MD; Susan M. Rubin, MPH; Virginia L. Ernster, PhD
JAMA. 1995;274(5):382-383. doi:10.1001/jama.1995.03530050028021.
Text Size: A A A
Published online


In Reply.  —Dr Hill argues that all of the randomized screening mammography trials that we pooled are flawed and should not be used to conclude that mammography is not beneficial for women aged 40 to 49 years. However, results from these same trials are used to support screening for women aged 50 to 69 years. Despite some cross-over and variation in type of intervention, all trials show a significant reduction in breast cancer mortality among screened women aged 50 to 74 years beginning at 7 to 9 years of follow-up. In contrast, among women aged 40 to 49 years, no pattern emerges among trials after 7 to 9 years of follow-up.Hill suggests that what is needed is an analysis of the raw data or a large randomized trial in women aged 40 to 49 years. While pooling raw data might answer some ancillary questions, the overall summary estimate is


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.