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November 25, 1983, Vol 250, No. 20 >
ARTICLE | November 25, 1983

Amount of Nicotine and Carbon Monoxide Inhaled by Smokers of Low-Tar, Low-Nicotine Cigarettes

Richard V. Ebert, MD; McKendree E. McNabb, MD; Kevin T. McCusker, MD; Sharon L. Snow
JAMA. 1983;250(20):2840-2842. doi:10.1001/jama.1983.03340200074034.
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In 76 smokers, correlations between plasma nicotine and alveolar carbon monoxide levels of the individual smoker and the nicotine and CO yields of his cigarette were very poor. In 24 smokers of low-nicotine, low-tar cigarettes, mean alveolar CO levels did not differ from those of smokers of regular cigarettes. Mean plasma nicotine levels were lower in smokers of low-nicotine cigarettes, but a wide overlap of individual values occurred. The implication that an individual shifting to ultra-low-tar cigarettes reduces risks of cardiopulmonary disease is unwarranted.

(JAMA 1983;250:2840-2842)

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