0
June 5, 1991, Vol 265, No. 21 >
ARTICLE | June 5, 1991

Malaria, Mefloquine, Madness, and Mosquito Nets-Reply

Hans O. Lobel, MD, MPH; Eve M. Lackritz, MD; Carlos C. Campbell, MD, MPH
JAMA. 1991;265(21):2808-2809. doi:10.1001/jama.1991.03460210054020.
Text Size: A A A
Published online
Article
References

In Reply. —  Choosing a drug for prophylaxis against malaria requires weighing the risk of malaria infection against the effectiveness and tolerance of the drug. Mefloquine is the most effective drug available to prevent infections with chloroquine-resistant Plasmodium falciparum malaria, a potentially fatal infection. Available data indicate that the drug is well tolerated when used for prophylaxis at doses of 250 mg. The frequency and type of mild or moderate adverse events reported by users of mefloquine for prophylaxis do not differ from those reported by users of chloroquine for prophylaxis.1,2 Anecdotal case reports suggest that serious neurological and psychiatric events, such as convulsions or hallucinations, are possible with mefloquine for prophylaxis; however, such events have not been reported from prophylactic drug trials or from surveys of users of mefloquine for prophylaxis.1-4 These studies included a total of 18 591 persons.2In contrast, therapeutic doses of mefloquine,

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

References

Letters

Submit a Letter
CME
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Clear Answers | Save For Later
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Compression-Only CPR: Pushing the Science Forward
Cone
AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs

More Listings at
JAMACareerCenter.com >

© 2013 American Medical Association. All Rights Reserved.
Powered bySilverchair Information Systems