0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Guidelines for Prophylaxis Against Pneumocystis carinii Pneumonia for Children Infected With Human Immunodeficiency Virus

JAMA. 1991;265(13):1637-1644. doi:10.1001/jama.1991.03460130027007.
Text Size: A A A
Published online

Extract

CDC.  Guidelines for prophylaxis against Pneumocystis carinii pneumonia for persons infected with human immunodeficiency virus . MMWR 1989;38 (no. (S-5) ).
Oxtoby MJ.  Perinatally acquired human immunodeficiency virus infection . Pediatr Infect Dis J 1990;9:609-19.
Scott GB, Hutto C, Makuch RW, et al.  Survival in children with perinatally acquired human immunodeficiency virus type 1 infection . N Engl J Med 1989;321:1791-6.
Link to Article[[XSLOpenURL/10.1056/NEJM198912283212604]]
Connor E, Bagarazzi M, McSherry G, et al.  Clinical and laboratory correlates of Pneumocystis carinii pneumonia in children infected with human immunodeficiency virus . JAMA 1991;265:1693-1697.
Link to Article[[XSLOpenURL/10.1001/jama.1991.03460130085027]]
Krasinski K, Borkowsky W, Holzman RS.  Prognosis of human immunodeficiency virus infection in children and adolescents . Pediatr Infect Dis J 1989;8:216-20.
Blanche S, Tardieu M, Duliege A-M, et al.  Longitudinal study of 94 symptomatic infants with perinatally acquired human immunodeficiency virus infection . Am J Dis Child 1990;144:1210-5.
Hsu H, Kunches L, Ng P, et al.  Pneumocystis carinii pneumonia in infants with HIV infection . (Abstract 417) 30th Interscience Conference on Antimicrobial Agents and Chemotherapy, Atlanta, GA, 1990 .
Kovacs A, Church J, Mascola L, et al.  CD4 counts as predictors of Pneumocystis carinii pneumonia in infants and children with HIV infection . JAMA 1991;265:1698-1703.
Link to Article[[XSLOpenURL/10.1001/jama.1991.03460130090028]]
Bernstein LJ, Bye MR, Rubinstein A.  Prognostic factors and life expectancy in children with acquired immunodeficiency syndrome and Pneumocystis carinii pneumonia . Am J Dis Child 1989;143:775-8.
Vernon DD, Holzman BH, Lewis P, et al.  Respiratory failure in children with acquired immunodeficiency syndrome and acquired immunodeficiency syndrome-related complex . Pediatrics 1988; 82:223-8.
Pahwa S.  Human immunodeficiency virus infection in children: nature of immunodeficiency, clinical spectrum and management . Pediatr Infect Dis J 1988;7:S61-71.
Link to Article[[XSLOpenURL/10.1097/00006454-198805001-00012]]
Rogers MF, Ou CY, Kilbourne B, et al.  Advances and problems in the diagnosis of HIV infection in infants . In: Pizzo PA, Wilfert CM, eds. Pediatric AIDS—The Challenge of HIV Infection in Infants, Children and Adolescents . Baltimore, MD: Williams & Wilkins, 1990:159-74.
Roilides E, Clerici M, DePalma L, Rubin M, Pizzo PA, Shearer GM.  T helper cell responses in children infected with human immunodeficiency virus type 1 . J Pediatr 1991 (in press).
Masur H, Ognibene F, Yarchoan R, et al.  CD4 counts as predictors of opportunistic pneumonias in human immunodeficiency virus (HIV) infection . Ann Intern Med 1989;111:223-31.
Link to Article[[XSLOpenURL/10.7326/0003-4819-111-3-223]]
Yanase Y, Tango T, Okumura K, et al.  Lymphocyte subsets identified by monoclonal antibodies in healthy children . Pediatr Res 1986;20:1147-51.
Link to Article[[XSLOpenURL/10.1203/00006450-198611000-00017]]
Denny TN, Niven P, Skuza C, et al.  Age-related changes of lymphocyte phenotypes in healthy children . (Abstract 916) Pediatr Res 1990;27:155A.
Link to Article[[XSLOpenURL/10.1203/00006450-199006001-00013]]
Leibovitz E, Rigaud M, Pollack H, et al.  Pneumocystis carinii pneumonia in infants infected with the human immunodeficiency virus with more than 450 CD4 T lymphocytes per cubic millimeter . N Engl J Med 1990;323:531-3.
Link to Article[[XSLOpenURL/10.1056/NEJM199008233230807]]
Sanders-Laufer D, Burroughs M, Marshall F, et al.  Pneumocystis carinii pneumonia (PCP) in "low-risk" HIV infected children  (Abstract 108) Pediatr Res 1990;27:183a.
Scott G, Buck BE, Leterman JG, et al.  Acquired immunodeficiency syndrome in infants . N Engl J Med 1984;310:76-81.
Link to Article[[XSLOpenURL/10.1056/NEJM198401123100202]]
Fischl MA, Dickinson GM, La Voie L.  Safety and efficacy of sulfamethoxazole and trimethoprim chemoprophylaxis for Pneumocystis carinii pneumonia in AIDS . JAMA 1988;259:1185-9.
Link to Article[[XSLOpenURL/10.1001/jama.259.8.1185]]
Hughes WT, Kuhn S, Chaudhary S, et al.  Successful chemoprophylaxis for Pneumocystis carinii pneumonitis . N Engl J Med 1977;297:1419-26.
Link to Article[[XSLOpenURL/10.1056/NEJM197712292972602]]
Hughes WT, Rivera GK, Schell MJ, et al.  Successful intermittent chemoprophylaxis for Pneumocystis carinii pneumonitis . N Engl J Med 1987;316:1627-32.
Link to Article[[XSLOpenURL/10.1056/NEJM198706253162604]]
Gutman LT.  The use of trimethoprim-sulfamethoxazole in children: a review of adverse reactions and indications . Pediatr Infect Dis J 1984;3:349-57.
Link to Article[[XSLOpenURL/10.1097/00006454-198407000-00018]]
Girdwood RH.  The nature of possible adverse reactions to co-trimoxazole . Scand J Infect Dis 1976;( (Suppl 8) ):10-17.
Asmar BI, Maqbool S, Dajani AS.  Hematologic abnormalities after oral trimethoprim-sulfamethoxazole therapy in children . Am J Dis Child 1980;135:1100-3.
Lawson DH, Paice BJ.  Adverse reactions to trimethoprim-sulfamethoxazole . Rev Infect Dis 1982;4:429-33.
Link to Article[[XSLOpenURL/10.1093/clinids/4.2.429]]
Jick H.  Adverse reactions to trimethoprim-sulphamethoxazole in hospitalized patients . Rev Infect Dis 1982;4:426-8.
Link to Article[[XSLOpenURL/10.1093/clinids/4.2.426]]
Gordin FM, Simon GL, Wofsy CB, et al.  Adverse reactions to trimethoprim-sulphamethoxazole in patients with the acquired immunodeficiency syndrome . Ann Intern Med 1984;100:495-9.
Link to Article[[XSLOpenURL/10.7326/0003-4819-100-4-495]]
Jaffe HS, Abrams DI, Ammann AJ, et al.  Complications of co-trimoxazole in treatment of AIDS-associated Pneumocystis carinii pneumonia in homosexual men . Lancet 1983;2:1109-11.
Link to Article[[XSLOpenURL/10.1016/S0140-6736(83)90627-X]]
McSherry G, Wright M, Oleske J, et al.  Frequency of serious adverse reactions to trimethoprim-sulfamethoxazole and pentamidine among children with human immunodeficiency virus 1 infection . (Abstract 1357) International Conference on Antimicrobial Agents and Chemotherapy, Los Angeles, CA, 1988 .
Leoung GS, Feigal DW, Montgomery AB, et al.  Aerosolized pentamidine for prophylaxis against Pneumocystis carinii pneumonia . N Engl J Med 1990;323:669-75.
Link to Article[[XSLOpenURL/10.1056/NEJM199009203231201]]
Corkery KJ, Luce JM, Montgomery AB.  Aerosolized pentamidine for treatment and prophylaxis of Pneumocystis carinii pneumonia: an update . Resp Care 1988;33:676-85.
 Diagnostic and therapeutic technology assessment (DATTA). Prophylactic treatment for opportunistic infections in HIV-positive patients: aerosolized pentamidine . JAMA 1990;263:2510-4.
Link to Article[[XSLOpenURL/10.1001/jama.1990.03440180120044]]
Martinez CM, Romanelli A, Mullen MP, et al.  Spontaneous pneumothoraces in AIDS patients receiving aerosolized pentamidine . (Letter) Chest 1988;94:1317-8.
Link to Article[[XSLOpenURL/10.1378/chest.94.6.1317b]]
Berger TG, Tappero JW, Leoung GS, et al.  Aerosolized pentamidine and cutaneous eruptions . (Letter) Ann Intern Med 1989;110:1035-6.
Link to Article[[XSLOpenURL/10.7326/0003-4819-110-12-1035_2]]
Lindley DA, Schleupner CJ.  Aerosolized pentamidine and conjunctivitis . (Letter) Ann Intern Med 1988;108:988.
Link to Article[[XSLOpenURL/10.7326/0003-4819-109-12-988_1]]
Herer B, Chinet T, Labrune S, et al.  Pancreatitis associated with pentamidine by aerosol . (Letter) Br Med J 1989;298:605.
Link to Article[[XSLOpenURL/10.1136/bmj.298.6673.605-a]]
Hart CC.  Aerosolized pentamidine and pancreatitis . (Letter) Ann Intern Med 1989;111:691.
Link to Article[[XSLOpenURL/10.7326/0003-4819-111-8-691_1]]
Chapelon C, Raguin G, De Gennes C.  Renal insufficiency with nebulised pentamidine . (Letter) Lancet 1989;2:1045-6.
Link to Article[[XSLOpenURL/10.1016/S0140-6736(89)91062-3]]
Karboski JA, Godley PJ.  Inhaled pentamidine and hypoglycemia . (Letter) Ann Intern Med 1988;108:490.
Link to Article[[XSLOpenURL/10.7326/0003-4819-108-3-490_1]]
Armstrong D, Bernard E.  Aerosolized pentamidine for the prevention and treatment of pneumocystosis . AIDS Updates 19903:1-7.
Abd AG, Nierman DM, Ilowite JS, et al.  Bilateral upper lobe Pneumocystis carinii pneumonia in a patient receiving inhaled pentamidine prophylaxis . Chest 1988;94:329-31.
Link to Article[[XSLOpenURL/10.1378/chest.94.2.329]]
Jules-Elysee KM, Stover DE, Zaman MB, et al.  Aerosolized pentamidine: effect on diagnosis and presentation of Pneumocystis carinii pneumonia . Ann Intern Med 1990;112:750-7.
Link to Article[[XSLOpenURL/10.7326/0003-4819-112-10-750]]
Northfelt DW.  Extrapulmonary pneumocystosis in patients taking aerosolized pentamidine . (Letter) Lancet 1989;2:1454.
Link to Article[[XSLOpenURL/10.1016/S0140-6736(89)92060-6]]
Problete RB, Rodriquez K, Foust RT, et al.  Pneumocystis carinii hepatitis in the acquired immunodeficiency syndrome (AIDS) . (Letter) Ann Intern Med 1989;110:737-8.
Link to Article[[XSLOpenURL/10.7326/0003-4819-110-9-737]]
Northfelt DW, Hardy WD.  Aerosolized pentamidine and disseminated infection with Pneumocystis carinii . (Letter) Ann Intern Med 1989;111:442-3.
Link to Article[[XSLOpenURL/10.7326/0003-4819-111-5-442]]
Sparling TG, Dong SR, Hegedus C, et al.  Aerosolized pentamidine and disseminated infection with Pneumocystis carinii . (Letter) Ann Intern Med 1989;111:442.
Link to Article[[XSLOpenURL/10.7326/0003-4819-111-5-442]]
CDC.  Advisory committee for the elimination of tuberculosis: tuberculosis and human immunodeficiency virus infection: recommendations . MMWR 1989;38:236-50.
CDC.  Mycobacterium tuberculosis: transmission in a health clinic—Florida, 1988 . MMWR 1989;38:256-8,263-4.
Metroka CE, Jacober D, Lewis N.  Successful chemoprophylaxis for pneumocystis with dapsone or bactrim  (Abstract T.B.O. 4) V International Conference on AIDS, Montreal, 1989 .
Torres R, Newlands J, Ortiz M, et al.  Randomized trial of intermittent dapsone versus aerosolized pentamidine for primary and secondary prophylaxis of PCP . (Abstract Th.B. 407) VI International AIDS Conference, San Francisco 1990 .
Salvin M, Hoy JF, Mijch AM, et al.  An open, randomized, prospective comparison of oral dapsone and nebulized pentamidine for PCP prophylaxis . (Abstract Th.B. 409) VI International AIDS Conference, San Francisco 1990 .
Kemper CA, Tucker RM, Lange OS, et al.  Low-dose dapsone prophylaxis of Pneumocystis carinii pneumonia in AIDS and AIDS-related complex . AIDS 1990;4:1145-8.
Link to Article[[XSLOpenURL/10.1097/00002030-199011000-00015]]
Hughes WT, Kennedy W, Dugdale M, et al.  Prevention of Pneumocystis carinii pneumonitis in AIDS patients with weekly dapsone . (Letter) Lancet 1990;2:1066.
Link to Article[[XSLOpenURL/10.1016/0140-6736(90)92533-N]]
Physician's Desk Reference , 45th Edition. Medical Economics Data, Oradell, NJ, 1991:1107-8.
Tomecki KJ, Catalano CJ.  Dapsone hypersensitivity: sulfone syndrome revisited . Arch Dermatol 1981;117:38-9.
Link to Article[[XSLOpenURL/10.1001/archderm.1981.01650010044023]]
Donnelly H, Bernard EM, Rothkotter H, et al.  Distribution of pentamidine in patients with AIDS . J Infect Dis 1988;157:985-9.
Link to Article[[XSLOpenURL/10.1093/infdis/157.5.985]]
Winslow D, Bincski A, Lincoln P, et al.  Secondary prophylaxis of Pneumocystis carinii pneumonia with systemic pentamidine . (Abstract T.B.P. 45) V International Conference on AIDS, Montreal 1989 .
Karaffa C, Rehm S, Calabrese L.  Efficacy of monthly pentamidine infusion in preventing recurrent Pneumocystis carinii pneumonia in AIDS patients . (Abstract 690). 26th Interscience Conference on Antimicrobial Agents and Chemotherapy, New Orleans, 1986 .
Miller S, Lifris D.  Efficacy of intramuscular pentamidine in the prophylaxis of recurrent Pneumocystis carinii pneumonia . (Abstract T.B.P. 60) V International Conference on AIDS, Montreal, 1989 .
Cheung T, Matta R, Neibart E, et al.  Intramuscular pentamidine for Pneumocystis carinii pneumonia prophylaxis . (Abstract 1) AIDS Clinical Trial Group Meeting, Washington, DC, November 1990 .
Institute of Medicine Committee on Prenatal and Newborn Screening for HIV infection. HIV screening of pregnant women and newborns . Washington, DC: National Academy Press, 1991.
Lewin EB.  Role of trimethoprim sulfamethoxazole in prophylaxis of recurrent otitis media . Pediatr Infect Dis J 1989;8:730-1. 669-75.
Link to Article[[XSLOpenURL/10.1097/00006454-198910000-00019]]

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();