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Group C β-Hemolytic Streptococci in College Students With Pharyngitis-Reply

James C. Turner, MD; Gregory F. Hayden, MD
JAMA. 1991;265(12):1526-1527. doi:10.1001/jama.1991.03460120040020.
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In Reply.—  Dr Waters and Ms Cook raise some interesting points. When we began our study, we lacked a priori evi dence that respiratory illnesses, if any, caused by non-group A streptococci would be clinically similar to those caused by the more familiar group A organisms. We cast a broad net, therefore, and included all patients with the chief complaint of sore throat. Based on the clinical features of our patients with group C isolates, it now appears that many patients with sore throat associated with group C streptococci have similar clinical features to those with group A isolates.To determine whether our original control group reliably reflects the actual carriage rate of group C streptococci, we have subsequently studied two additional populations of healthy controls. We have found a virtually identical isolation rate (12%) of group C streptococci on throat culture in a total of 250 healthy students at


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